Sakura Mikan and Imai Hotaru are best friends, and Mikan is shocked to find that Hotaru is transferring to a school in Tokyo for gifted students like her—Alice Academy. Mikan hears rumors that the students are like prisoners there, and worried what would happen to Hotaru, she runs away to head to the school herself. She finds out all the wonderful things about this school. And she heads into a great adventure!!